antiphospholipid syndrome

Other Disorders

Liver Disease

 

Obstructive disease

- decreased absorption Vitamin K as it is fat soluble

- Vit K dependent factors affected

- II, VII, IX & X 

- raised INR

 

Hepatocellular Disease

- impairs synthesis of all coagulation proteins

- bleeding episodes treated with FFP or Cryoprecipitate

 

Vit K Deficiency

 

Occurs with impaired intake or malabsorption