Chronic, non metabolic bone disorder
Characterised by increased bone resorption, bone formation and remodelling
Rare < 40
1 – 3 % population over 60
M > F
Unknown
Paramyxovirus implicated
- measles
- RSV
- canine distemper virus
Electron Microscope
Lumbar spondylosis
- disc degeneration causing arthritis / lower back pain
Discogenic lower back pain
Annulus fibrosis
- outer aspect of disc
- type I collagen
- fibres continuous with endplate & ALL/PLL
A HLA B27 positive, seronegative spondyloarthropathy with sacroiliac joint & spine involvement
Mainly affects the cartilaginous joints of the axial skeleton
1. Positive X-ray Sacroiliitis
