factor VIII replacement

Hemophilia

Definition

 

Hereditary bleeding disorder due to defective and/or deficient factor VIII molecule

 

Inherited X-linked recessive disorder

- occurs almost solely in males

- female carriers usually asymptomatic

- 30% have no family history

 

Haemophilia A

 

FVIII deficiency

 

X-linked disorder

- 1:10 000

- all ethnic groups