CT Scan



Irradiate a slice of tissue from multiple angles


Measure the output from different sides


Tissues have different densities

- with denser tissue fewer x-rays reach the detectors


Hounsfield scale


Bone    2000

ST        40

Water   0

Fat       -100

Air       -1000

Undifferentiated Pleomorphic Sarcoma



Malignant Fibrous Histiocytoma


Characterised by heterogenous population of pleomorphic spindle cells

- organised in a characteristic storiform or "starry night" pattern


Cell of origin unknown 

- primitive mesenchymal cell

- allowing both features of a macrophage (hence histiocyte)

- and collagen producing cell (hence fibroblast)